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Replication, Fine-Mapping and Sequencing: Follow-Up on Genome-Wide Association Studies for Arthritis and Musculoskeletal and Skin Diseases (R01)

Department of Health and Human Services

 
Synopsis
       


The synopsis for this grant opportunity is detailed below, following this paragraph. This synopsis contains all of the updates to this document that have been posted as of 03/20/2009 . If updates have been made to the opportunity synopsis, update information is provided below the synopsis.

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Document Type: Grants Notice
Funding Opportunity Number: PAR-09-135
Opportunity Category: Discretionary
Posted Date: Mar 20, 2009
Creation Date: Mar 20, 2009
Original Closing Date for Applications: Jun 29, 2011   
Current Closing Date for Applications: Jun 29, 2011   
Archive Date: Jul 30, 2011
Funding Instrument Type: Grant
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards:
Estimated Total Program Funding: $1,500,000
Award Ceiling: $250,000
Award Floor:
CFDA Number(s): 93.846  --  Arthritis, Musculoskeletal and Skin Diseases Research
Cost Sharing or Matching Requirement: No

Eligible Applicants

State governments
County governments
City or township governments
Special district governments
Independent school districts
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
For profit organizations other than small businesses
Small businesses
Others (see text field entitled "Additional Information on Eligibility" for clarification)
 

Additional Information on Eligibility:

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Agency Name

National Institutes of Health

Description

Purpose. This Funding Opportunity Announcement (FOA), issued by the National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, encourages applications that propose to perform replication, fine-mapping, and sequencing studies of human genomic regions that are putatively associated with phenotypes relevant to the NIAMS mission. Genomic regions of interest are primarily those identified by genome-wide association studies (GWAS). The objective of this FOA is to enhance the identification of causal genes and genetic variants that influence complex diseases relevant to the NIAMS mission. Replication, fine-mapping, and sequencing studies are to be conducted in existing cohorts with defined phenotypes. This FOA will not support recruitment of human subjects, collection of medical or phenotypic data, studies using animal models, or the initial discovery phase of GWAS. Mechanism of Support. This FOA will utilize the NIH Research Project (R01) grant mechanism. In some instances, an active NIAMS R01 award may currently support a GWAS with a two-stage design, including initial discovery and replication. In such instances, investigators may submit a revision (formerly competing supplement) application in response to this FOA, to support additional replication, fine-mapping, or sequencing efforts, provided the application conforms to both the budgetary requirements of this FOA and the format requirements of revision applications. Funds Available and Anticipated Number of Awards. For this funding opportunity, the NIAMS expects to commit approximately $1.5 million total costs in each of fiscal years 2010, 2011, and 2012, to support three to four new projects per year. Budgets up to $250,000 direct costs per year and project periods of up to two years may be requested. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.

Link to Full Announcement

http://grants.nih.gov/grants/guide/pa-files/PAR-09-135.html

If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

Synopsis Modification History

There are currently no modifications for this opportunity.