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06/18/2009
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Document Type:
Grants Notice
Funding Opportunity Number:
W81XWH-09-PRCRP-CA
Opportunity Category:
Discretionary
Posted Date:
Jun 18, 2009
Creation Date:
Jun 18, 2009
Original Closing Date for Applications:
Jul 30, 2009
Current Closing Date for Applications:
Jul 30, 2009
Archive Date:
Aug 29, 2009
Funding Instrument Type:
Cooperative Agreement
Grant
Category of Funding Activity:
Science and Technology and other Research and Development
Category Explanation:
Expected Number of Awards:
11
Estimated Total Program Funding:
$1,300,000
Award Ceiling:
Award Floor:
CFDA Number(s):
12.420
--
Military Medical Research and Development
Cost Sharing or Matching Requirement:
No
Eligible Applicants
Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"
Additional Information on Eligibility:
Agency Name
Dept. of the Army -- USAMRAA
Description
The PRCRP Concept Award supports the exploration of a highly innovative new concept or untested theory. The Concept Award is not intended to support a logical progression of an already
established research project but, instead, supports high-risk studies that have the potential to reveal entirely new avenues for investigation. Research completed through a Concept Award may provide sufficient preliminary data to enable the Principal Investigator (PI) to prepare a proposal for future research.
Presentation of preliminary data is not allowed. However, a rationale for the work must be
provided.
For FY09, the Concept Award is being offered in two congressionally directed topic areas:
(1) Noninvasive cancer ablation research including selective targeting with nano-particles, and (2) genetic cancer research and its relation to exposure to the various environments that are unique to a military lifestyle. No other topic areas will be allowed. Proposals must not address breast, prostate, or ovarian cancer research. Focus Areas for each of the two topic areas are provided in this Program Announcement/Funding Opportunity. Applications to the FY09 PRCRP Concept Award will be rated on their responsiveness to the following Focus Areas for each of the two topic areas.
Focus Areas for Genetic Cancer Research:
 Identification and characterization of changes in gene structure and/or gene expression resulting from physical, biological, or chemical exposures and stressful environments that, alone or in concert, are known or suspected to increase cancer risk. Although not all inclusive, hazards
encountered by the military population include:
o Radiation (UV and other radiation sources)
o Biological Agents
o Chemicals
o Physical and Psychological Stress
o Other Environmental Conditions (e.g., noise, heat, altitude)
 Investigation of biological pathways involved in carcinogenic mechanisms which are affected by
military exposures
 Investigation of the trans-generational cancer risk of military exposures
 Evaluation of differences in genetic susceptibility to cancer among ethnic groups affected by military exposures
Focus Areas for Noninvasive Cancer Ablation:
 Development of approaches for deep organ access for ablation technologies
 Validation of nanoparticle targeting
For applications in the topic area of Genetic Cancer Research, it is the responsibility of the
applicant to clearly and explicitly articulate the project’s military relevance.
See the Program Announcement for the full Funding Opportunity Description.
Link to Full Announcement
If you have difficulty accessing the full announcement
electronically, please contact:
PA HELP: 301-619-7079; cdmrp.pa@amedd.army.mil
eReceipt HELP: 301-682-5507; help@cdmrp.org
CDMRP Helpdesk
Synopsis Modification History
There are currently no modifications for this opportunity.
