The synopsis for this grant opportunity is detailed below, following
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document that have been posted as of
08/14/2009
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Document Type:
Grants Notice
Funding Opportunity Number:
RFA-DK-09-011
Opportunity Category:
Discretionary
Posted Date:
Aug 14, 2009
Creation Date:
Aug 14, 2009
Original Closing Date for Applications:
Nov 23, 2009
Current Closing Date for Applications:
Nov 23, 2009
Archive Date:
Dec 24, 2009
Funding Instrument Type:
Cooperative Agreement
Category of Funding Activity:
Food and Nutrition
Health
Category Explanation:
Expected Number of Awards:
Estimated Total Program Funding:
$12,000,000
Award Ceiling:
Award Floor:
CFDA Number(s):
93.847
--
Diabetes, Endocrinology and Metabolism Research
Cost Sharing or Matching Requirement:
No
Eligible Applicants
State governments
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
For profit organizations other than small businesses
Small businesses
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility:
Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Non-domestic (non-U.S.) Entities (Foreign Organizations); Tribally Controlled Colleges and Universities (TCCUs) .
Agency Name
National Institutes of Health
Description
Purpose. The National Institute of Diabetes and Digestive and Kidney Diseases invite new U01 applications to participate in a consortium of investigators, the Beta Cell Biology Consortium (BCBC); www.betacell.org . The BCBC will work collaboratively to facilitate research in the following areas: 1) use cues from pancreatic development to directly differentiate pancreatic beta cells and islets from stem/progenitor cells for use in cell-replacement therapies for diabetes; 2) determine how to stimulate beta cell regeneration in the adult pancreas as a basis for improving beta cell mass in diabetic patients; 3) determine how to reprogram progenitor/adult cells into pancreatic beta-cells both in-vitro and in-vivo as a mean for developing cell-replacement therapies for diabetes; and 4) investigate the progression of human type-1 diabetes using patient-derived cells and tissues transplanted in humanized mouse models. The BCBC will be responsible for collaboratively generating the necessary reagents, mouse strains, antibodies, assays, protocols, technologies and validation assays that are beyond the scope of any single research effort proposed by the investigators.
Mechanism of Support. This FOA will utilize the U01 grant mechanism.
Funds Available and Anticipated Number of Awards. The total amount of funding that the NIDDK expects to award through this announcement in FY2010 is $12 million. The anticipated number of awards is 6-10. Although the financial plans of the NIDDK provide support for the first two years of this program, awards pursuant to this FOA, particularly in years 3 to 5 of the awards, are contingent upon the availability of funds.
