The synopsis for this grant opportunity is detailed below, following
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document that have been posted as of
10/06/2009
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Document Type:
Grants Notice
Funding Opportunity Number:
EPA-G2009-STAR-H1
Opportunity Category:
Discretionary
Posted Date:
Oct 06, 2009
Creation Date:
Oct 06, 2009
Original Closing Date for Applications:
Jan 07, 2010
Please refer to the full announcement, including Section IV, for additional information on submission methods and due dates.
Current Closing Date for Applications:
Jan 07, 2010
Please refer to the full announcement, including Section IV, for additional information on submission methods and due dates.
Archive Date:
Feb 06, 2010
Funding Instrument Type:
Grant
Category of Funding Activity:
Environment
Category Explanation:
Expected Number of Awards:
4
Estimated Total Program Funding:
$1,700,000
Award Ceiling:
$425,000
Award Floor:
CFDA Number(s):
66.509
--
Science To Achieve Results (STAR) Research Program
Cost Sharing or Matching Requirement:
No
Eligible Applicants
State governments
County governments
City or township governments
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility:
See Section III of the announcement for additional eligibility information.
Agency Name
Environmental Protection Agency
Description
The U.S. Environmental Protection Agency (EPA), as part of its Science to Achieve Results (STAR) program, is issuing this request for applications (RFA) for applied research on innovative or improved methods to predict whether or not a pesticide protein is a food allergen. Research to characterize the key factors that influence human immune responses to dietary proteins is needed in order to better assess potential food allergy from genetically engineered plants. Proposals are requested on the role of dose, route of sensitization, and/or the physicochemical properties of ingested proteins and their influence on the development of immune sensitization, oral tolerance, or the elicitation of allergic symptoms. Also of interest is how the food matrix and gastrointestinal environment in which proteins are ingested may affect these immune responses. The overall aim of the research program is to improve safety assessment for genetically engineered plants by enhancing the ability to estimate the potency of unknown proteins relative to known allergenic and non-allergenic proteins. Because there is no single, definitive test for determining the allergenic potential of novel pesticide proteins in the diet, risk assessment associated with the regulation of foods derived from modern biotechnology currently uses a “weight-of-evidence” approach. The research will contribute to improved methods for assessing the potential dietary allergenicity of pesticide proteins in genetically engineered plants.
