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Immunoregulation of Gastrointestinal Carcinogenesis (R01)

Department of Health and Human Services

 
Synopsis
       


The synopsis for this grant opportunity is detailed below, following this paragraph. This synopsis contains all of the updates to this document that have been posted as of 12/21/2006 . If updates have been made to the opportunity synopsis, update information is provided below the synopsis.

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Document Type: Grants Notice
Funding Opportunity Number: PA-07-256
Opportunity Category: Discretionary
Posted Date: Dec 21, 2006
Creation Date: Dec 05, 2008
Original Closing Date for Applications: Multiple Receipt Dates - See Link to Full Announcement for details.
Current Closing Date for Applications: Multiple Receipt Dates - See Link to Full Announcement for details.
Archive Date: Jun 01, 2009
Funding Instrument Type: Grant
Category of Funding Activity: Education
Health
Category Explanation:
Expected Number of Awards:
Estimated Total Program Funding:
Award Ceiling:
Award Floor:
CFDA Number(s): 93.393  --  Cancer Cause and Prevention Research
93.396  --  Cancer Biology Research
Cost Sharing or Matching Requirement: No

Eligible Applicants

State governments
County governments
City or township governments
Special district governments
Independent school districts
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
For profit organizations other than small businesses
Small businesses
Others (see text field entitled "Additional Information on Eligibility" for clarification)
 

Additional Information on Eligibility:

Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith-based or community-based organizations can apply.

Agency Name

National Institutes of Health

Description

-Purpose. This Funding Opportunity Announcement (FOA) issued by the National Cancer Institute (NCI), National Institutes of Health (NIH), solicits grant applications from researchers interested in the investigations of two aspects of gastrointestinal carcinogenesis, which include: (1) the roles of the mucosal immune system in initiating and maintaining inflammatory responses that contribute to the development of premalignant and malignant gastrointestinal cancers; and/or (2) the molecular mechanism(s) by which immunoregulatory cells dampen inflammation and decrease tumorigenesis. Applications submitted in response to this FOA should be focused on research that will increase our understanding of how the unique gastrointestinal microenvironment shapes mucosal immune responses in the setting of inflammatory disease-associated carcinogenesis. The ultimate goal of this scientific initiative is to generate a comprehensive understanding of how the innate and adaptive immune responses participate in gastrointestinal carcinogenesis. -Mechanism of Support. This FOA will utilize the NIH Research Project Grant (R01) award mechanism and runs in parallel with an FOA of identical scientific scope, PA-06-290, that solicits applications under the Exploratory/Developmental Grant (R21) award mechanism. -Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.

Link to Additional Information

http://grants.nih.gov/grants/guide/pa-files/PA-07-256.html

If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

Synopsis Modification History

There are currently no modifications for this opportunity.