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Exfoliated Cells, Bioactive Food Components, and Cancer (R21)

Department of Health and Human Services

 
Synopsis
       


The synopsis for this grant opportunity is detailed below, following this paragraph. This synopsis contains all of the updates to this document that have been posted as of 11/26/2007 . If updates have been made to the opportunity synopsis, update information is provided below the synopsis.

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Document Type: Grants Notice
Funding Opportunity Number: PA-08-031
Opportunity Category: Discretionary
Posted Date: Nov 26, 2007
Creation Date: Dec 05, 2008
Original Closing Date for Applications: Jan 07, 2011   
Current Closing Date for Applications: Jan 07, 2011   
Archive Date: Feb 07, 2011
Funding Instrument Type: Grant
Category of Funding Activity: Education
Health
Category Explanation:
Expected Number of Awards:
Estimated Total Program Funding:
Award Ceiling:
Award Floor:
CFDA Number(s): 93.399  --  Cancer Control
Cost Sharing or Matching Requirement: No

Eligible Applicants

State governments
Public and State controlled institutions of higher education
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
For profit organizations other than small businesses
Small businesses
Others (see text field entitled "Additional Information on Eligibility" for clarification)
 

Additional Information on Eligibility:

Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Regional Organization

Agency Name

National Institutes of Health

Description

Purpose. The National Cancer Institute (NCI) invites applications for new R21 grants that focus on research to critically evaluate the use of exfoliated cells to monitor the physiological effects of dietary bioactive food components thought to be involved with cancer prevention. The objective is to encourage interdisciplinary collaborations between scientists engaged in research using exfoliated cells and those conducting nutrition research related to cancer prevention. This research will help determine the utility of exfoliated cells as a model system to monitor both the absorption and retention of bioactive food components and the concomitant alterations in genomic and epigenetic events that occur in intact cells. Mechanism of Support. This FOA utilizes the NIH Exploratory/Developmental Grant (R21) mechanism and runs in parallel with an FOA of identical scientific scope, PA-08-030, that solicits applications under the NIH Research Project Grant (R01) mechanism. The R21 grant is not renewable. Funds Available and Anticipated number of Awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received. Budget and Project Period: The total project period for an application submitted in response to this funding opportunity may not exceed 2 years. Direct costs are limited to $275,000 over an R21 2-year period, with no more than $200,000 in direct costs allowed in any single year. Eligible organizations: Public/State Controlled Institution of Higher Education; Private Institution of Higher Education; Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education); Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education); Small Business; For-Profit Organizations (Other than Small Business); State Governments; U.S. Territory or Possession; Non-Domestic (non-U.S.) Entity (Foreign Organization); Regional Organization; Eligible agencies of the Federal government Eligible Project Directors/Principal Investigators (PDs/PIs): Any individuals from the applicant institutions who have the skills, knowledge, and resources necessary to carry out the proposed research. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support. Renewals. R21 awards are not renewable. Resubmissions. Up to two resubmissions (formerly revisions/amendments") of a previously reviewed R21 grant application may be submitted. Application and Submission Information: Applicants may submit more than one application, provided each application is scientifically distinct.

Link to Additional Information

http://grants.nih.gov/grants/guide/pa-files/PA-08-031.html

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Synopsis Modification History

There are currently no modifications for this opportunity.