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Funding Opportunity Number:
Jul 18, 2008
Dec 05, 2008
Original Closing Date for Applications:
Sep 07, 2011
Current Closing Date for Applications:
Sep 07, 2011
Oct 08, 2011
Funding Instrument Type:
Category of Funding Activity:
Expected Number of Awards:
Estimated Total Program Funding:
Cancer Cause and Prevention Research
Cancer Biology Research
Cost Sharing or Matching Requirement:
Public and State controlled institutions of higher education
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
For profit organizations other than small businesses
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility:
Other Eligible Applicants include the following:
Eligible Agencies of the Federal Government; Hispanic-serving Institutions; Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; U.S. Territory or Possession.
National Institutes of Health
-Purpose. This funding opportunity announcement (FOA), issued by the National Cancer Institute (NCI), encourages the submission of grant applications that describe research projects focused on the identification and characterization of diet-induced changes in inflammation linked to colon cancer risks. This FOA is designed to stimulate research efforts that will lead to the identification and characterization of: diet-induced changes in anti- and pro-inflammatory mediators that modulate colon cancer risk; b) genetic polymorphisms that modify the responses to specific bioactive food components with regard to colon cancer inhibition; and c) the physiological effectiveness of dietary components in terms of concentration, activity, duration of exposure, degrees of stability, chemical forms, and receptor-binding affinity in inflammatory colonocytes. This FOA will not support applications that propose epidemiological studies based on diet-related risks of colon cancer.
-Mechanism of Support. This FOA uses the NIH research project R01 grant mechanism and runs in parallel with an FOA of identical scientific scope, PA-08-211, that solicits applications under the NIH Exploratory/Developmental (R21) Grant mechanism.
-Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.