The synopsis for this grant opportunity is detailed below, following
this paragraph. This synopsis contains all of the updates to this
document that have been posted as of
08/23/2012
. If
updates have been made to the opportunity synopsis, update information
is provided below the synopsis.
If you would like to receive notifications of changes to the grant
opportunity click
send
me change notification emails
.
The only thing you need to provide for this service is your email
address. No other information is requested.
Any inconsistency between the original printed document and the disk
or electronic document shall be resolved by giving precedence to the
printed document.
Document Type:
Grants Notice
Funding Opportunity Number:
RFA-ES-12-008
Opportunity Category:
Discretionary
Posted Date:
Aug 23, 2012
Creation Date:
Aug 23, 2012
Original Closing Date for Applications:
Nov 19, 2012
Current Closing Date for Applications:
Nov 19, 2012
Archive Date:
Dec 20, 2012
Funding Instrument Type:
Grant
Category of Funding Activity:
Education
Environment
Health
Category Explanation:
Expected Number of Awards:
5
Estimated Total Program Funding:
$3,000,000
Award Ceiling:
$400,000
Award Floor:
CFDA Number(s):
93.113
--
Environmental Health
93.279
--
Drug Abuse and Addiction Research Programs
Cost Sharing or Matching Requirement:
No
Eligible Applicants
State governments
County governments
City or township governments
Special district governments
Independent school districts
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
For profit organizations other than small businesses
Small businesses
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility:
Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.
Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Agency Name
National Institutes of Health
Description
In order to understand the mechanisms by which toxicants impact gene expression, it is necessary to better understand how exposure affects the proteins and processes upstream of DNA methylation and other epigenetic marks. The NIEHS has made a significant investment in research aimed at identifying epigenetic signatures of exposure, but the mechanistic studies aimed at identifying how these epigenetic marks are established are currently under-represented in our portfolio. The purpose of this FOA is to encourage research applications that will potentially move the field from descriptive and correlative studies to an enhanced mechanistic understanding of how environmental exposures affect the proteins and functional genomic elements involved in establishing and maintaining gene expression patterns and chromatin states.
