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Document Type:
Grants Notice
Funding Opportunity Number:
W81XWH-10-NFRP-EHDA
Opportunity Category:
Discretionary
Posted Date:
Mar 02, 2010
Creation Date:
Mar 02, 2010
Original Closing Date for Applications:
May 20, 2010
Current Closing Date for Applications:
May 20, 2010
Archive Date:
Jun 19, 2010
Funding Instrument Type:
Cooperative Agreement
Grant
Category of Funding Activity:
Science and Technology and other Research and Development
Category Explanation:
Expected Number of Awards:
5
Estimated Total Program Funding:
$750,000
Award Ceiling:
Award Floor:
CFDA Number(s):
12.420
--
Military Medical Research and Development
Cost Sharing or Matching Requirement:
No
Eligible Applicants
Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"
Additional Information on Eligibility:
Agency Name
Dept. of the Army -- USAMRAA
Description
The NFRP Exploration – Hypothesis Development Award (EHDA) mechanism was first offered in FY08. Since that time, 46 EHDA applications have been received, and 13 have been recommended for funding.
The EHDA supports the initial exploration of innovative, high-risk, high-gain, and potentially groundbreaking concepts in the neurofibromatosis and/or Schwannomatosis research fields. Results of studies conducted through this award may provide the scientific rationale upon which a new hypothesis can be based, or they should provide initial principles of an innovative hypothesis. This award is designed to provide investigators with the opportunity to pursue serendipitous observations. The presentation of preliminary data is encouraged, but not required.
It is the responsibility of the Principal Investigator (PI) to clearly and explicitly articulate how the proposed research is innovative and how the concept is novel.
DOD FY10 Neurofibromatosis Exploration – Hypothesis Development Award 3
Because these awards are designed for preliminary investigations, projects involving human subjects or specimens will not be supported unless they are exempt under 32 CFR 219.101(b) or eligible for expedited review (32 CFR 219.110 or 21 CFR 56.110). Additional information on the protection of human subjects and exempt or expedited review status may be found at https://www.bids.tswg.gov/TSWG/bids.nsf/5DD5E2BA50F02C18852572B1005F5B8B/$file/Title_32_CFR_Part_219.pdf. Applications proposing studies that do not qualify for exempt or expedited review status will be administratively withdrawn. PIs wishing to apply for funding for a clinical trial should utilize the Clinical Trial Award mechanism.
Areas of Encouragement: The FY10 NFRP encourages research proposals that specifically address the critical needs of the NF community in the following areas:
• Complications of NF with high mortality such as neoplasms and cerebrovascular abnormalities;
• Complications of NF with high morbidity such as skeletal maladies, learning deficits, hormone-associated effects, and pain;
• Refinement and standardization of imaging techniques, molecular and cellular markers, and quality of life metrics for use in future clinical trials; and
• Translational research such as the development or preclinical testing of therapeutic agents for the treatment of NF.
Link to Additional Information
If you have difficulty accessing the full announcement
electronically, please contact:
PA HELP: 301-619-7079; cdmrp.pa@amedd.army.mil
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CDMRP Help Desk
Synopsis Modification History
There are currently no modifications for this opportunity.
